Lateral Diffusion of Proteins on Supported Lipid Bilayers: Additive Friction of Synaptotagmin 7 C2A–C2B Tandem Domains

[Image: see text] The synaptotagmin (Syt) family of proteins contains tandem C2 domains, C2A and C2B, which bind membranes in the presence of Ca(2+) to trigger vesicle fusion during exocytosis. Despite recent progress, the role and extent of interdomain interactions between C2A and C2B in membrane b...

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Bibliographic Details
Published in:Biochemistry
Main Authors: Vasquez, Joseph K., Chantranuvatana, Kan, Giardina, Daniel T., Coffman, Matthew D., Knight, Jefferson D.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2014
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278679/
https://ncbi.nlm.nih.gov/pubmed/25437758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi5012223
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