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Conformation and Membrane Position of the Region Linking the two C2 Domains in Synaptotagmin 1 by Site-Directed Spin Labeling
Synaptotagmin 1 (syt1) is an integral membrane protein localized on the synaptic vesicle that acts as the Ca(2+) sensor for neuronal exocytosis. Synaptotagmin 1 contains two C2 domains, C2A and C2B, which bind Ca(2+) ions, membranes and SNAREs. Here, site-directed-spin-labeling (SDSL) was used to de...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2661311/ https://ncbi.nlm.nih.gov/pubmed/18956883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801470m |
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