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Phosphatidylinositol 4,5 bisphosphate alters Synaptotagmin 1 Membrane Docking and Drives Opposing Bilayers Closer Together

Synaptotagmin 1 (syt1) is a synaptic vesicle-anchored membrane protein that acts as the calcium sensor for the synchronous component of neuronal exocytosis. Using site-directed spin labeling, the position and membrane interactions of a fragment of syt1 containing its two C2 domains (syt1C2AB) were d...

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Autors principals: Kuo, Weiwei, Herrick, Dawn Z., Cafiso, David S.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071796/
https://ncbi.nlm.nih.gov/pubmed/21344950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200049c
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