Nalaganje...
Phosphatidylinositol 4,5-Bisphosphate Increases Ca(2+) Affinity of Synaptotagmin-1 by 40-fold
Synaptotagmin-1 is the main Ca(2+) sensor of neuronal exocytosis. It binds to both Ca(2+) and the anionic phospholipid phosphatidylinositol 4,5-bisphosphate (PIP(2)), but the precise cooperativity of this binding is still poorly understood. Here, we used microscale thermophoresis to quantify the coo...
Shranjeno v:
| Main Authors: | , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2012
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3351315/ https://ncbi.nlm.nih.gov/pubmed/22447935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.343418 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|