Synaptotagmin-1 may be a distance regulator acting upstream of SNARE nucleation

Synaptotagmin-1 triggers Ca(2+)-sensitive, rapid neurotransmitter release by promoting the interaction of SNARE proteins between the synaptic vesicles and the plasma membrane. How synaptotagmin-1 promotes this interaction is controversial, and the massive increase in membrane fusion efficiency of Ca...

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Main Authors: van den Bogaart, Geert, Thutupalli, Shashi, Risselada, Jelger H., Meyenberg, Karsten, Holt, Matthew, Riedel, Dietmar, Diederichsen, Ulf, Herminghaus, Stephan, Grubmüller, Helmut, Jahn, Reinhard
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130798/
https://ncbi.nlm.nih.gov/pubmed/21642968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2061
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