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Phosphatidylinositol 4,5 Bisphosphate Controls the cis and trans Interactions of Synaptotagmin 1

Synaptotagmin 1 acts as the Ca(2+) sensor for synchronous neurotransmitter release; however, the mechanism by which it functions is not understood and is presently a topic of considerable interest. Here, we describe measurements on full-length membrane-reconstituted synaptotagmin 1 using site-direct...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Nyenhuis, Sarah B., Thapa, Anusa, Cafiso, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6701194/
https://ncbi.nlm.nih.gov/pubmed/31301806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.06.016
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