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The Calcium-Dependent and Calcium-Independent Membrane Binding of Synaptotagmin 1: Two Modes of C2B Binding

The Ca(2+)-independent membrane interactions of the soluble C2 domains from synaptotagmin 1 (syt1) were characterized using a combination of site-directed spin labeling (SDSL) and vesicle sedimentation. The second C2 domain of syt1, C2B, binds to membranes containing phosphatidylserine (PS) and phos...

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Main Authors: Kuo, Weiwei, Herrick, Dawn Z., Ellena, Jeffrey F., Cafiso, David S.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669496/
https://ncbi.nlm.nih.gov/pubmed/19302798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.01.064
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