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The Calcium-Dependent and Calcium-Independent Membrane Binding of Synaptotagmin 1: Two Modes of C2B Binding
The Ca(2+)-independent membrane interactions of the soluble C2 domains from synaptotagmin 1 (syt1) were characterized using a combination of site-directed spin labeling (SDSL) and vesicle sedimentation. The second C2 domain of syt1, C2B, binds to membranes containing phosphatidylserine (PS) and phos...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2669496/ https://ncbi.nlm.nih.gov/pubmed/19302798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.01.064 |
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