C-terminal domain of SARS-CoV main protease can form a 3D domain-swapped dimer

SARS coronavirus main protease (M(pro)) plays an essential role in the extensive proteolytic processing of the viral polyproteins (pp1a and pp1ab), and it is an important target for anti-SARS drug development. We have reported that both the M(pro) C-terminal domain alone (M(pro)-C) and the N-finger...

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Bibliographische Detailangaben
Hauptverfasser: Zhong, Nan, Zhang, Shengnan, Xue, Fei, Kang, Xue, Zou, Peng, Chen, Jiaxuan, Liang, Chao, Rao, Zihe, Jin, Changwen, Lou, Zhiyong, Xia, Bin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley Subscription Services, Inc., A Wiley Company 2009
Schlagworte:
Protein Structure Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762595/
https://ncbi.nlm.nih.gov/pubmed/19319935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.76
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