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Transcriptional IL-15-Directed in vivo DC Targeting DNA Vaccine
DC engineered in vitro by DNA encoding OVAhsp70 and IL-15 up-regulated their expressions of CD80, CD86, CCR7 and IL-15Rα and promoted their productions of IL-6, IL-12 and TNF-α. Transcriptional IL-15-directed in vivo DC targeting DNA vaccine encoding OVAhsp70 elicited long-lasting Th1 and CTL respon...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2762487/ https://ncbi.nlm.nih.gov/pubmed/19727134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2009.110 |
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