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Combined IL-15/IL-15Rα Immunotherapy Maximizes IL-15 Activity In Vivo

IL-15 has substantial potential as an immunotherapeutic agent for augmenting immune responses. However, the activity of IL-15 is mediated by a unique mechanism in which the cytokine is transpresented by cell-bound high-affinity IL-15Rα to target cells expressing the IL-15Rβ and the common γ-chain. T...

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Bibliografski detalji
Glavni autori: Stoklasek, Thomas A., Schluns, Kimberly S., Lefrançois, Leo
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847275/
https://ncbi.nlm.nih.gov/pubmed/17056533
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