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Sprouty2 association with B-Raf is regulated by phosphorylation and kinase conformation

Sprouty2 is a feedback regulator that controls the Ras-Raf-MEK-ERK mitogen-activated protein kinase (MAPK) pathway at multiple levels, one way being through direct interaction with Raf kinases. Consistent with a role as a tumor suppressor, Sprouty2 expression is often down-regulated in human cancers...

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Detaylı Bibliyografya
Asıl Yazarlar: Brady, Suzanne C., Coleman, Mathew L., Munro, June, Feller, Stephan M., Morrice, Nicolas A., Olson, Michael F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762204/
https://ncbi.nlm.nih.gov/pubmed/19690147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4447
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