INHIBITION OF SOLUBLE EPOXIDE HYDROLASE DOES NOT PROTECT AGAINST ENDOTOXIN-MEDIATED HEPATIC INFLAMMATION

Epoxyeicosatrienoic acids (EETs) are derived from cytochrome P450 (CYP)-catalyzed epoxygenation of arachidonic acid and have emerged as important mediators of numerous biological effects. The major elimination pathway for EETs is through soluble epoxide hydrolase (sEH) catalyzed metabolism to dihydr...

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Detaylı Bibliyografya
Asıl Yazarlar: Fife, Kimberly L., Liu, YingMei, Schmelzer, Kara R., Tsai, Hsing-Ju, Kim, In-Hae, Morisseau, Christophe, Hammock, Bruce D., Kroetz, Deanna L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761654/
https://ncbi.nlm.nih.gov/pubmed/18815352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.142398
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