Novel structural determinants in human SECIS elements modulate the translational recoding of UGA as selenocysteine

The selenocysteine insertion sequence (SECIS) element directs the translational recoding of UGA as selenocysteine. In eukaryotes, the SECIS is located downstream of the UGA codon in the 3′-UTR of the selenoprotein mRNA. Despite poor sequence conservation, all SECIS elements form a similar stem-loop...

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Detalles Bibliográficos
Autores principales: Latrèche, Lynda, Jean-Jean, Olivier, Driscoll, Donna M., Chavatte, Laurent
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2009
Materias:
RNA
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761289/
https://ncbi.nlm.nih.gov/pubmed/19651878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp635
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