Functional characterization of the eukaryotic SECIS elements which direct selenocysteine insertion at UGA codons.

We investigated the requirements for selenocysteine insertion at single or multiple UGA codons in eukaryotic selenoproteins. Two functional SECIS elements were identified in the 3' untranslated region of the rat selenoprotein P mRNA, with predicted stem-loops and critical nucleotides similar to...

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Publicat a:EMBO J
Autors principals: Berry, M J, Banu, L, Harney, J W, Larsen, P R
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1993
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413599/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8344267/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb06001.x
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