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Identification of the Selenoprotein S Positive UGA Recoding (SPUR) element and its position-dependent activity

Selenoproteins are a unique class of proteins that contain the 21st amino acid, selenocysteine (Sec). Addition of Sec into a protein is achieved by recoding of the UGA stop codon. All 25 mammalian selenoprotein mRNAs possess a 3′ UTR stem-loop structure, the Selenocysteine Insertion Sequence (SECIS)...

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Autors principals: Eric M. Cockman, Vivek Narayan, Belinda Willard, Sumangala P. Shetty, Paul R. Copeland, Donna M. Driscoll
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis Group 2024-12-01
Col·lecció:RNA Biology
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Accés en línia:https://www.tandfonline.com/doi/10.1080/15476286.2019.1653681
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