Novel structural determinants in human SECIS elements modulate the translational recoding of UGA as selenocysteine

The selenocysteine insertion sequence (SECIS) element directs the translational recoding of UGA as selenocysteine. In eukaryotes, the SECIS is located downstream of the UGA codon in the 3′-UTR of the selenoprotein mRNA. Despite poor sequence conservation, all SECIS elements form a similar stem-loop...

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Hlavní autoři: Latrèche, Lynda, Jean-Jean, Olivier, Driscoll, Donna M., Chavatte, Laurent
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
RNA
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761289/
https://ncbi.nlm.nih.gov/pubmed/19651878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp635
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