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Novel structural determinants in human SECIS elements modulate the translational recoding of UGA as selenocysteine

The selenocysteine insertion sequence (SECIS) element directs the translational recoding of UGA as selenocysteine. In eukaryotes, the SECIS is located downstream of the UGA codon in the 3′-UTR of the selenoprotein mRNA. Despite poor sequence conservation, all SECIS elements form a similar stem-loop...

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Bibliografske podrobnosti
Main Authors: Latrèche, Lynda, Jean-Jean, Olivier, Driscoll, Donna M., Chavatte, Laurent
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2009
Teme:
RNA
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761289/
https://ncbi.nlm.nih.gov/pubmed/19651878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp635
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