Φορτώνει......
Formation of a unique end-to-end stacked pair of G-quadruplexes in the hTERT core promoter with implications for inhibition of telomerase by G-quadruplex-interactive ligands
The hTERT core promoter contains a G-rich region of 12 consecutive G-tracts, embracing three Sp1 binding sites, and has the potential to form multiple G-quadruplexes. From the 12 runs of guanine tracts, 9 putative hTERT G-quadruplex-forming sequences were selected to assay for G-quadruplex formation...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2009
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2761083/ https://ncbi.nlm.nih.gov/pubmed/19601575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja902281d |
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