The hTERT core promoter forms three parallel G-quadruplexes

The structure of the 68 nt sequence with G-quadruplex forming potential within the hTERT promoter is disputed. One model features a structure with three stacked parallel G-quadruplex units, while another features an unusual duplex hairpin structure adjoined to two stacked parallel and antiparallel q...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Monsen, Robert C, DeLeeuw, Lynn, Dean, William L, Gray, Robert D, Sabo, T Michael, Chakravarthy, Srinivas, Chaires, Jonathan B, Trent, John O
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2020
Materias:
Structural Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261196/
https://ncbi.nlm.nih.gov/pubmed/32083666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa107
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