טוען...
An Improved Model for the hTERT Promoter Quadruplex
Mutations occur at four specific sites in the hTERT promoter in >75% of glioblastomas and melanomas, but the mechanism by which the mutations affect gene expression remains unexplained. We report biophysical computational studies that show that the hTERT promoter sequence forms a novel G-quadrupl...
שמור ב:
| הוצא לאור ב: | PLoS One |
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| Main Authors: | , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4272262/ https://ncbi.nlm.nih.gov/pubmed/25526084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115580 |
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