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Polyethylene glycol binding alters human telomere G-quadruplex structure by conformational selection
Polyethylene glycols (PEGs) are widely used to perturb the conformations of nucleic acids, including G-quadruplexes. The mechanism by which PEG alters G-quadruplex conformation is poorly understood. We describe here studies designed to determine how PEG and other co-solutes affect the conformation o...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3763525/ https://ncbi.nlm.nih.gov/pubmed/23804761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt440 |
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