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Lineage fate and intense debate: myths, models and mechanisms of CD4/CD8 lineage choice
Following successful gene rearrangement at αβ T-cell receptor (TCR) loci, developing thymocytes express both CD4 and CD8 co-receptors and undergo a life-or-death selection event known as positive selection to identify cells expressing TCRs with potentially useful ligand specificities. Positively sel...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2760737/ https://ncbi.nlm.nih.gov/pubmed/18802443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri2416 |
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