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MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication

Mutations in RECQ4, a member of the RecQ family of DNA helicases, have been linked to the progeroid disease Rothmund–Thomson Syndrome. Attempts to understand the complex phenotypes observed in recq4-deficient cells suggest a potential involvement in DNA repair and replication, yet the molecular basi...

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Hlavní autoři: Xu, Xiaohua, Rochette, Patrick J, Feyissa, Eminet A, Su, Tina V, Liu, Yilun
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760112/
https://ncbi.nlm.nih.gov/pubmed/19696745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.235
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