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Mcm10 regulates DNA replication elongation by stimulating the CMG replicative helicase
Activation of the Mcm2–7 replicative DNA helicase is the committed step in eukaryotic DNA replication initiation. Although Mcm2–7 activation requires binding of the helicase-activating proteins Cdc45 and GINS (forming the CMG complex), an additional protein, Mcm10, drives initial origin DNA unwindin...
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| Publicado no: | Genes Dev |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5358725/ https://ncbi.nlm.nih.gov/pubmed/28270517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.291336.116 |
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