Ciprofloxacin is an inhibitor of the Mcm2-7 replicative helicase

Most currently available small molecule inhibitors of DNA replication lack enzymatic specificity, resulting in deleterious side effects during use in cancer chemotherapy and limited experimental usefulness as mechanistic tools to study DNA replication. Towards development of targeted replication inh...

Full description

Saved in:
Bibliographic Details
Main Authors: Simon, Nicholas, Bochman, Matthew L., Seguin, Sandlin, Brodsky, Jeffrey L., Seibel, William L., Schwacha, Anthony
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2013
Subjects:
Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791872/
https://ncbi.nlm.nih.gov/pubmed/24001138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20130083
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items