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Ciprofloxacin is an inhibitor of the Mcm2-7 replicative helicase

Most currently available small molecule inhibitors of DNA replication lack enzymatic specificity, resulting in deleterious side effects during use in cancer chemotherapy and limited experimental usefulness as mechanistic tools to study DNA replication. Towards development of targeted replication inh...

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Detalhes bibliográficos
Main Authors: Simon, Nicholas, Bochman, Matthew L., Seguin, Sandlin, Brodsky, Jeffrey L., Seibel, William L., Schwacha, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791872/
https://ncbi.nlm.nih.gov/pubmed/24001138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20130083
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