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The Mcm Complex: Unwinding the Mechanism of a Replicative Helicase

Summary: The Mcm2-7 complex serves as the eukaryotic replicative helicase, the molecular motor that both unwinds duplex DNA and powers fork progression during DNA replication. Consistent with its central role in this process, much prior work has illustrated that Mcm2-7 loading and activation are lan...

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Detalhes bibliográficos
Main Authors: Bochman, Matthew L., Schwacha, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786579/
https://ncbi.nlm.nih.gov/pubmed/19946136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MMBR.00019-09
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