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The Mcm Complex: Unwinding the Mechanism of a Replicative Helicase

Summary: The Mcm2-7 complex serves as the eukaryotic replicative helicase, the molecular motor that both unwinds duplex DNA and powers fork progression during DNA replication. Consistent with its central role in this process, much prior work has illustrated that Mcm2-7 loading and activation are lan...

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Библиографические подробности
Главные авторы: Bochman, Matthew L., Schwacha, Anthony
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786579/
https://ncbi.nlm.nih.gov/pubmed/19946136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MMBR.00019-09
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