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Subunit Organization of Mcm2-7 and the Unequal Role of Active Sites in ATP Hydrolysis and Viability

The Mcm2-7 (minichromosome maintenance) complex is a toroidal AAA(+) ATPase and the putative eukaryotic replicative helicase. Unlike a typical homohexameric helicase, Mcm2-7 contains six distinct, essential, and evolutionarily conserved subunits. Precedence to other AAA(+) proteins suggests that Mcm...

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Detaylı Bibliyografya
Asıl Yazarlar: Bochman, Matthew L., Bell, Stephen P., Schwacha, Anthony
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2547011/
https://ncbi.nlm.nih.gov/pubmed/18662997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00161-08
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