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ATP Binding and Hydrolysis by Mcm2 Regulate DNA Binding by Mcm Complexes
The essential minichromosome maintenance (Mcm) proteins Mcm2 through Mcm7 likely comprise the replicative helicase in eukaryotes. In addition to Mcm2–7, other subcomplexes, including one comprising Mcm4, Mcm6, and Mcm7, unwind DNA. Using Mcm4/6/7 as a tool, we reveal a role for nucleotide binding by...
Enregistré dans:
| Publié dans: | J Mol Biol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5154746/ https://ncbi.nlm.nih.gov/pubmed/19540846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.06.038 |
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