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Temporal Correlation of DNA Binding, ATP Hydrolysis, and Clamp Release in the Clamp Loading Reaction Catalyzed by the Escherichia coli γ complex
Clamp loaders are multi-subunit complexes that use the energy derived from ATP binding and hydrolysis to assemble ring-shaped sliding clamps onto DNA. Sliding clamps in turn tether DNA polymerases to the templates being copied to increase the processivity of DNA synthesis. Here, the rate of clamp re...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2759312/ https://ncbi.nlm.nih.gov/pubmed/19663416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900912a |
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