Overexpression of Mn Superoxide Dismutase Does Not Increase Life Span in Mice

Genetic manipulations of Mn superoxide dismutase (MnSOD), SOD2 expression have demonstrated that altering the level of MnSOD activity is critical for cellular function and life span in invertebrates. In mammals, Sod2 homozygous knockout mice die shortly after birth, and alterations of MnSOD levels a...

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Detaylı Bibliyografya
Asıl Yazarlar: Jang, Youngmok C., Pérez, Viviana I., Song, Wook, Lustgarten, Michael S., Salmon, Adam B., Mele, James, Qi, Wenbo, Liu, Yuhong, Liang, Hanyu, Chaudhuri, Asish, Ikeno, Yuji, Epstein, Charles J., Van Remmen, Holly, Richardson, Arlan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2009
Konular:
Journal of Gerontology: Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759571/
https://ncbi.nlm.nih.gov/pubmed/19633237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glp100
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