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Overexpression of Mn Superoxide Dismutase Does Not Increase Life Span in Mice
Genetic manipulations of Mn superoxide dismutase (MnSOD), SOD2 expression have demonstrated that altering the level of MnSOD activity is critical for cellular function and life span in invertebrates. In mammals, Sod2 homozygous knockout mice die shortly after birth, and alterations of MnSOD levels a...
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| Autori principali: | , , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2759571/ https://ncbi.nlm.nih.gov/pubmed/19633237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glp100 |
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