Macrophage Antigen Complex-1 Mediates Reactive Microgliosis and Progressive Dopaminergic Neurodegeneration in the MPTP Model of Parkinson's Disease

Neuronal death is known to trigger reactive microgliosis. However, little is known regarding the manner by which microglia are activated by injured neurons and how microgliosis participates in neurodegeneration. In this study we delineate the critical role of macrophage Ag complex-1 (MAC1), a member...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Hu, Xiaoming, Zhang, Dan, Pang, Hao, Caudle, W. Michael, Li, Yachen, Gao, Huiming, Liu, Yuxin, Qian, Li, Wilson, Belinda, Monte, Donato A. Di, Ali, Syed F., Zhang, Jing, Block, Michelle L., Hong, Jau-Shyong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759089/
https://ncbi.nlm.nih.gov/pubmed/18981141
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items