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Reactive microgliosis: extracellular μ-calpain and microglia-mediated dopaminergic neurotoxicity
Microglia, the innate immune cells in the brain, can become chronically activated in response to dopaminergic neuron death, fuelling a self-renewing cycle of microglial activation followed by further neuron damage (reactive microgliosis), which is implicated in the progressive nature of Parkinson’s...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2860703/ https://ncbi.nlm.nih.gov/pubmed/20123724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awp333 |
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