Squamosamide derivative FLZ protects dopaminergic neurons against inflammation-mediated neurodegeneration through the inhibition of NADPH oxidase activity

BACKGROUND: Inflammation plays an important role in the pathogenesis of Parkinson's disease (PD) through over-activation of microglia, which consequently causes the excessive production of proinflammatory and neurotoxic factors, and impacts surrounding neurons and eventually induces neurodegene...

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Autori principali: Zhang, Dan, Hu, Xiaoming, Wei, Sung-Jen, Liu, Jie, Gao, Huiming, Qian, Li, Wilson, Belinda, Liu, Gengtao, Hong, Jau-Shyong
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2413210/
https://ncbi.nlm.nih.gov/pubmed/18507839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-5-21
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