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Critical Role for Microglial NADPH Oxidase in Rotenone-Induced Degeneration of Dopaminergic Neurons

Increasing evidence has suggested an important role for environmental toxins such as pesticides in the pathogenesis of Parkinson's disease (PD). Chronic exposure to rotenone, a common herbicide, reproduces features of Parkinsonism in rats. Mechanistically, rotenone-induced dopaminergic neurodeg...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Gao, Hui-Ming, Liu, Bin, Hong, Jau-Shyong
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740554/
https://ncbi.nlm.nih.gov/pubmed/12867501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-15-06181.2003
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