Macrophage Antigen Complex-1 Mediates Reactive Microgliosis and Progressive Dopaminergic Neurodegeneration in the MPTP Model of Parkinson's Disease

Neuronal death is known to trigger reactive microgliosis. However, little is known regarding the manner by which microglia are activated by injured neurons and how microgliosis participates in neurodegeneration. In this study we delineate the critical role of macrophage Ag complex-1 (MAC1), a member...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Hu, Xiaoming, Zhang, Dan, Pang, Hao, Caudle, W. Michael, Li, Yachen, Gao, Huiming, Liu, Yuxin, Qian, Li, Wilson, Belinda, Monte, Donato A. Di, Ali, Syed F., Zhang, Jing, Block, Michelle L., Hong, Jau-Shyong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759089/
https://ncbi.nlm.nih.gov/pubmed/18981141
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky