Translation inhibitors stabilize Escherichia coli mRNAs independently of ribosome protection

Translation inhibitors such as chloramphenicol in prokaryotes or cycloheximide in eukaryotes stabilize many or most cellular mRNAs. In Escherichia coli, this stabilization is ascribed generally to the shielding of mRNAs by stalled ribosomes. To evaluate this interpretation, we examine here how inhib...

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Bibliografske podrobnosti

izdano v:	Proc Natl Acad Sci U S A
Principais autores:	Lopez, P. J., Marchand, I., Yarchuk, O., Dreyfus, M.
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 1998
Teme:	Biological Sciences
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27586/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9600918/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.11.6067
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