Inhibition of Ribosome Assembly and Ribosome Translation Has Distinctly Different Effects on Abundance and Paralogue Composition of Ribosomal Protein mRNAs in Saccharomyces cerevisiae

ABSTRACT Many mutations in genes for ribosomal proteins (r-proteins) and assembly factors cause cell stress and altered cell fate, resulting in congenital diseases collectively called ribosomopathies. Even though all such mutations depress the cell’s protein synthesis capacity, they generate many di...

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Detalhes bibliográficos

Principais autores:	Md Shamsuzzaman, Nusrat Rahman, Brian Gregory, Ananth Bommakanti, Janice M. Zengel, Vincent M. Bruno, Lasse Lindahl
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2023-02-01
coleção:	mSystems
Assuntos:	cell stress nucleolar stress ribosomal protein paralogues ribosomal proteins ribosome biogenesis transcriptome
Acesso em linha:	https://journals.asm.org/doi/10.1128/msystems.01098-22
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