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Leaderless mRNAs Bind 70S Ribosomes More Strongly than 30S Ribosomal Subunits in Escherichia coli

By primer extension inhibition assays, 70S ribosomes bound with higher affinity, or stability, than did 30S subunits to leaderless mRNAs containing AUG or GUG start codons. Addition of translation initiation factors affected ribosome binding to leaderless mRNAs. Our results suggest that translation...

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Detalles Bibliográficos
Main Authors: O'Donnell, Sean M., Janssen, Gary R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC135410/
https://ncbi.nlm.nih.gov/pubmed/12426363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.23.6730-6733.2002
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