Leaderless mRNAs Bind 70S Ribosomes More Strongly than 30S Ribosomal Subunits in Escherichia coli

By primer extension inhibition assays, 70S ribosomes bound with higher affinity, or stability, than did 30S subunits to leaderless mRNAs containing AUG or GUG start codons. Addition of translation initiation factors affected ribosome binding to leaderless mRNAs. Our results suggest that translation...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	O'Donnell, Sean M., Janssen, Gary R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Genetics and Molecular Biology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135410/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12426363/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.184.23.6730-6733.2002
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