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Genes for highly abundant proteins in Escherichia coli avoid 5' codons that promote ribosomal initiation.

In many species highly expressed genes (HEGs) over-employ the synonymous codons that match the more abundant iso-acceptor tRNAs. Bacterial transgene codon randomization experiments report, however, that enrichment with such "translationally optimal" codons has little to no effect on the resultant pr...

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I tiakina i:
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Ngā kaituhi matua: Loveday E Lewin, Kate G Daniels, Laurence D Hurst
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Public Library of Science (PLoS) 2023-10-01
Rangatū:PLoS Computational Biology
Urunga tuihono:https://doi.org/10.1371/journal.pcbi.1011581
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