Translation inhibitors stabilize Escherichia coli mRNAs independently of ribosome protection

Translation inhibitors such as chloramphenicol in prokaryotes or cycloheximide in eukaryotes stabilize many or most cellular mRNAs. In Escherichia coli, this stabilization is ascribed generally to the shielding of mRNAs by stalled ribosomes. To evaluate this interpretation, we examine here how inhib...

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Cyhoeddwyd yn:	Proc Natl Acad Sci U S A
Prif Awduron:	Lopez, P. J., Marchand, I., Yarchuk, O., Dreyfus, M.
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	National Academy of Sciences 1998
Pynciau:	Biological Sciences
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27586/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9600918/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.11.6067
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