Translation inhibitors stabilize Escherichia coli mRNAs independently of ribosome protection

Translation inhibitors such as chloramphenicol in prokaryotes or cycloheximide in eukaryotes stabilize many or most cellular mRNAs. In Escherichia coli, this stabilization is ascribed generally to the shielding of mRNAs by stalled ribosomes. To evaluate this interpretation, we examine here how inhib...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Lopez, P. J., Marchand, I., Yarchuk, O., Dreyfus, M.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1998
Materias:	Biological Sciences
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27586/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9600918/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.11.6067
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