Učitavanje...
Removal of B cell epitopes as a practical approach for reducing the immunogenicity of foreign protein-based therapeutics
Immunogenicity of non-human proteins with useful therapeutic properties has prevented their development for use in the therapy of disease. However, this class of proteins could be very useful, if their immunogenicity could be markedly reduced so that many treatment cycles could be administered. One...
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| Glavni autori: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2757538/ https://ncbi.nlm.nih.gov/pubmed/19679153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2009.07.014 |
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