NV-128, a novel isoflavone derivative, induces caspase-independent cell death through Akt/mTOR pathway

BACKGROUND: Resistance to apoptosis is one of the key events that confer chemo-resistance and is mediated by over-expression of anti-apoptotic proteins, which inhibit caspase activation. The objective of this study was to evaluate whether the activation of an alternative cell death pathway (caspase-...

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Detaylı Bibliyografya
Asıl Yazarlar: Alvero, Ayesha B., Montagna, Michele K., Chen, Rui, Kim, Ki Hyung, Kyungjin, Kim, Visintin, Irene, Fu, Han-Hsuan, Brown, David, Mor, Gil
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757274/
https://ncbi.nlm.nih.gov/pubmed/19472400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.24397
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