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NV-128, a novel isoflavone derivative, induces caspase-independent cell death through Akt/mTOR pathway
BACKGROUND: Resistance to apoptosis is one of the key events that confer chemo-resistance and is mediated by over-expression of anti-apoptotic proteins, which inhibit caspase activation. The objective of this study was to evaluate whether the activation of an alternative cell death pathway (caspase-...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2757274/ https://ncbi.nlm.nih.gov/pubmed/19472400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.24397 |
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