Caricamento...
Increased inflammatory gene expression in ABC transporter deficient macrophages: free cholesterol accumulation, increased signaling via Toll-like receptors and neutrophil infiltration of atherosclerotic lesions
BACKGROUND: Two macrophage ABC transporters, ABCA1 and ABCG1 have a major role in promoting cholesterol efflux from macrophages. Peritoneal macrophages deficient in ABCA1 and/or ABCG1 show enhanced expression of inflammatory and chemokine genes. This study was undertaken to elucidate the mechanisms...
Salvato in:
| Autori principali: | , , , , , , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2756536/ https://ncbi.nlm.nih.gov/pubmed/18852364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.793869 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|