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Cholesterol, inflammation and innate immunity
Hypercholesterolaemia leads to cholesterol accumulation in macrophages and other immune cells, which promotes inflammatory responses, including augmentation of Toll-like receptor (TLR) signalling, inflammasome activation, and the production of monocytes and neutrophils in the bone marrow and spleen....
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| Published in: | Nat Rev Immunol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4669071/ https://ncbi.nlm.nih.gov/pubmed/25614320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri3793 |
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