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Cholesterol, inflammation and innate immunity

Hypercholesterolaemia leads to cholesterol accumulation in macrophages and other immune cells, which promotes inflammatory responses, including augmentation of Toll-like receptor (TLR) signalling, inflammasome activation, and the production of monocytes and neutrophils in the bone marrow and spleen....

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Detalhes bibliográficos
Publicado no:Nat Rev Immunol
Main Authors: Tall, Alan R., Yvan-Charvet, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669071/
https://ncbi.nlm.nih.gov/pubmed/25614320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri3793
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