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Regulation of hematopoietic stem and progenitor cell mobilization by cholesterol efflux pathways

Intact cholesterol homeostasis helps to maintain hematopoietic stem and multipotential progenitor cell (HSPC) quiescence. Mice with defects in cholesterol efflux pathways due to deficiencies of the ATP binding cassette transporters ABCA1 and ABCG1 displayed a dramatic increase in HSPC mobilization a...

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Bibliografiska uppgifter
Huvudupphovsmän: Westerterp, Marit, Gourion-Arsiquaud, Samuel, Murphy, Andrew J, Shih, Alan, Cremers, Serge, Levine, Ross L., Tall, Alan R, Yvan-Charvet, Laurent
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413200/
https://ncbi.nlm.nih.gov/pubmed/22862945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.04.024
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