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Regulation of hematopoietic stem and progenitor cell mobilization by cholesterol efflux pathways
Intact cholesterol homeostasis helps to maintain hematopoietic stem and multipotential progenitor cell (HSPC) quiescence. Mice with defects in cholesterol efflux pathways due to deficiencies of the ATP binding cassette transporters ABCA1 and ABCG1 displayed a dramatic increase in HSPC mobilization a...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3413200/ https://ncbi.nlm.nih.gov/pubmed/22862945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.04.024 |
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